National Renewable Energy Laboratory Researcher III – Science in Golden, Colorado
Researcher III – Science
CO - Golden
Limited Term (Fixed Term)
Hours Per Week
Microorganisms have proven themselves as useful chassis for the production of compounds of interest. While the production of native molecules has been successful for millennia (eg. ethanol), new technologies for strain engineering have enabled the production of non-native products with complicated chemistries. Despite significant advances in technology, the underlying engineering goal remains to rewire an organism to re-route metabolism toward the desired product. This goal inherently contradicts evolutionary pressures, substantially complicating strain engineering. The objective of the work relating to this position will probe various ways of circumventing evolutionary pressures relating to decreased bioproductivity of genetically engineered organisms.
Job responsibilities include the following:
Design of DNA constructs for the manipulation of prokaryotic metabolism
Metabolic pathway analysis for the production of novel compounds
Optimize metabolic pathways for non-native product formation
Perform chromatin immunoprecipitation and DNA sequencing
Effectively communicate and interact with scientists and engineers to accomplish project goals
Disseminate knowledge through publications in technical journals. Provide reports on technical work and input to technical publications and presentations.
Work with management and senior staff to plan and design projects.
Must have a PhD degree in Chemical and Biomolecular Engineering, Molecular Biology, Applied Chemistry, Biochemistry, Microbiology or a closely related field.
Must have a minimum of 2 years of work experience post graduation.
Additional Required Qualifications
A strong publication in the peer-reviewed scientific literature
Demonstrated experience communicating results at national/international conferences
Ability to work independently and in teams to deliver high-quality results within aggressive timelines.
Strong background in molecular and microbiology
Proficiency in bioreactor cultivations, protein engineering, systems biology, and analytical tool development
Demonstrates complete understanding and wide application of scientific technical procedures, principles, theories and concepts in the field. General knowledge of other related disciplines. Demonstrates leadership in one or more areas of team, task or project lead responsibilities. Demonstrated experience in management of projects. Very good technical writing, interpersonal and communication skills.
- Prior work experience at a national laboratory
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The National Renewable Energy Laboratory (NREL) is a leader in the U.S. Department of Energy’s effort to secure an environmentally and economically sustainable energy future. With locations in Golden and Boulder, Colorado, and a satellite office in Washington, D.C., NREL is the primary laboratory for research, development, and deployment of renewable energy technologies in the United States.
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